Receptor-ligand kinetics for research and drug discovery

Introduction Receptor-ligand interactions are molecular binding events that alter receptor activity or trigger a response in the cell. Researchers are interested in studying receptor-ligand interactions to understand how cells communicate with their environment and how they operate in response to cell signaling . Receptor-ligand interactions are also an important target for drug discovery (Fig. 1) due to their pivotal role in cell biology . 1-4 Significantly, receptors are one of the largest cla