Exercise prescription for mood and cognition: targeting the microbiota-gut-brain axis through short-chain fatty acids
Xiaoyan Chen
Scientific study has extensively corroborated the advantageous impacts of exercise on mood, cognitive function, and stress resilience. Nonetheless, the fundamental biological mechanisms underpinning these effects have yet to be thoroughly integrated. This review advocates for and substantiates an integrated model focused on the “Exercise-Gut Microbiome-Short-Chain Fatty Acids (SCFAs)-Brain Function” axis. Consistent physical exercise alters the gut microbiota, enhancing Short-Chain Fatty Acid (S