Characterizing the metabolomes of microglia, astrocytes and neurons in ageing and Alzheimer’s brains
Woo-ping Ge
Nature Cell Biology, Published online: 30 April 2026; doi:10.1038/s41556-026-01910-2 Yu, Li and colleagues explore the metabolome of neurons, microglia and astrocytes under normal, ageing and Alzheimer’s disease conditions. They find enrichment of glutathione and polyamine metabolism in microglia, which decreased with ageing and in Alzheimer’s disease.