Electroconvulsive therapy modulates Fronto-temporal functional connectivity in adolescents with depression and suicidal ideation
Li Kuang
ObjectiveWe aimed to investigate changes in whole-brain functional connectivity (FC) before and after electroconvulsive therapy (ECT) in adolescents with major depressive disorder (MDD) and suicidal ideation (SI).MethodsForty-nine adolescents with MDD and SI were enrolled, and resting-state functional magnetic resonance imaging (rs-fMRI) was performed at baseline and after ECT for each patient. Forty healthy controls (HCs) were scanned only at baseline. Region-of-interest (ROI)-based whole-brain