Cyproheptadine enhances weight gain and modulates appetite-regulating peptides in children with failure to thrive and food allergies

BackgroundCyproheptadine hydrochloride (CH) possesses both antihistaminic and appetite-stimulating properties, suggesting therapeutic potential for children with failure to thrive (FTT) and food allergies. This study evaluated the effects of CH on growth parameters, clinical manifestations, and serum levels of appetite-regulating peptides Nesfatin-1 and NUCB2 in children aged 1–3 years with FTT and food allergy.MethodsIn this non-randomized controlled real-world study, participants were assigned