BackgroundA better understanding of the response of granulosa cells to exogenous hormone stimulation and how this impacts the complex interplay between the granulosa cells and the oocyte is crucial for the optimal management of infertile couples seeking IVF treatment.MethodsGranulosa and cumulus cells (G + CCs) from women with different degrees of ovarian responsiveness to controlled ovarian hyperstimulation (COH) were purified and used for RNA sequencing (RNA-seq) analysis and downstream bioinf