Genomic and virulence characterization of OXA-48-producing Klebsiella pneumoniae causing urinary tract infections and their susceptibility to lytic bacteriophages

IntroductionKlebsiella pneumoniae (Kpn) is the second most frequent cause of urinary tract infections (UTIs) and represents a major concern in the context of antimicrobial resistance (AMR); nevertheless, the phenotypic and genomic traits that define uropathogenic Kpn strains are not clear.MethodsIn this study, 24 carbapenemase-producing Kpn strains, most of them (23/24) carrying blaOXA-48, isolated from urine samples of nosocomial or community origin in northwest Spain, were characterized in ter