Stabilised G protein-coupled receptors in structure-based drug design: a case study with adenosine A2A receptor
James Anson
This review from the MedChemComm New Talent themed issue covers one of the first successful examples of structure-based drug design for stabilised G protein-coupled receptors (GPCRs), focusing on the development of a pre-clinical candidate for the treatment of Parkinson’s disease using StaR® technology. Stabilised G protein-coupled receptors in structure-based drug design: a case study with […]