Characterization and phage-antibiotic synergy of bacteriophages PES-1 and PES-2 against porcine enterotoxigenic Escherichia coli
Lili Wang
The emergence of drug-resistant porcine enterotoxigenic Escherichia coli (ETEC) necessitates the exploration of alternative antibacterial approaches. Two lytic bacteriophages, PES-1 and PES-2, have been isolated and characterized to control ETEC. PES-1 exhibited a wide host range, lysing five ETEC strains, whereas PES-2 displayed restricted specificity, impacting only one of the seven strains. Both phages demonstrated optimal stability at a pH of 4.0–7.0 and a temperature of 4 °C–37 °C. Comparat