PCSK9 inhibitors are some of the most effective LDL-lowering drugs out there, but they’ve all required injection, and some even refrigeration. That just changed, however, with the FDA’s approval of Merck’s Lipfendra (enlicitide), the first ever oral PCSK9i. Budding from the CORALreef trial series, including the Lipids and HeFH readouts, Lipfendra’s approval rests on a […] The post An Oral PCSK9i and What it Means for Merck appeared first on Cardiac Wire .