Malignant tumor is still one of the most critical diseases in clinic. Current therapeutic strategies include surgery, chemoradiotherapy, targeted therapy, and immunotherapy. Nevertheless, the development of novel drugs with superior efficacy and reduced drug toxicity remains a goal for researchers. The rise of nanomedicine has injected new momentum into oncology treatment. Among nano-platforms, metal-polyphenol materials can be engineered into nanodots, nanospheres or network structures, which c