Gadolinium-based contrast agent-free (GBCA-free) versus gadolinium-based contrast agent-enhanced (GBCA-enhanced) magnetic resonance imaging as a screening tool for intracranial tumors

BackgroundGBCA-enhanced MRI is considered the gold standard for diagnosing intracranial tumors. However, concerns regarding gadolinium-based contrast agents (GBCAs) and workflow limitations have led to increasing interest in GBCA-free MRI techniques.ObjectiveTo compare the diagnostic performance of GBCA-free MRI with GBCA-enhanced MRI for detecting intracranial tumors within a neurological diagnostic pathway.MethodsIn this retrospective cohort study, 191 patients with 195 tumors (124 intra-axial