Immunopeptidome Analysis for Peptide Identification by Mass Spectrometry
Life in the Lab Staff
Immunopeptidome analysis enables the comprehensive identification of major histocompatibility complex (MHC)-bound peptides to better understand antigen presentation and immune recognition. By combining targeted immunoprecipitation workflows with high-resolution peptide identification by mass spectrometry, researchers can characterize thousands of MHC-associated peptides with high sensitivity and reproducibility. Advances in standardized enrichment strategies, automation, and Orbitrap-based LC-MS