Cerium-based nanozymes for chemodynamic therapy: tumor microenvironment-responsive mechanisms and applications
Qian Liu
Cerium-based nanozymes (CeNZs) are a class of nanomaterials possessing enzyme-like catalytic activities. Their unique Ce3+/Ce4+ redox pair and multi-enzyme mimicking activities make them highly advantageous for tumor chemodynamic therapy (CDT). This review systematically summarizes recent research progress in the application of CeNZs for tumor CDT. It focuses on their multi-enzyme catalytic mechanisms and the intelligent regulation of their catalytic behavior by the tumor microenvironment. Furth