Epigenetic reprogramming of T cell metabolism restores function and enhances anti-tumor immunity in lung cancer
Hsing-Chen Tsai
Nature Immunology, Published online: 12 May 2026; doi:10.1038/s41590-026-02515-5 Tsai and colleagues propose that BET inhibitors can blunt T cell exhaustion via a pathway involving ornithine decarboxylase-dependent polyamine biosynthesis.