Nature Medicine, Published online: 19 August 2026; doi:10.1038/s41591-026-04601-5 A pilot implementation study of a large language model clinical decision support system in a tertiary emergency department showed safe integration but steadily declining clinical adoption over 4 weeks.
Nature Medicine, Published online: 19 August 2026; doi:10.1038/s41591-026-04589-y Liver DiagnOsis Network (LiON), a contrast-enhanced-computed tomography-based AI system that supports flexible multiphase processing, clinical data integration and workflow-compatible liver malignancy diagnosis, may help reduce missed or delayed diagnoses and guide clinical interventions.
BackgroundTraditional Chinese Medicine (TCM) rheumatology presents unique challenges for AI-assisted clinical decision support, as the diagnostic process relies heavily on tacit knowledge and individualized reasoning. While Large Language Models (LLMs) have shown promise in medical applications, they remain limited by hallucination risks and inability to replicate expert TCM reasoning. Retrieval-…
One of the earliest stated goals for computing in medicine was to aid in clinical reasoning: the decision-making steps required to reach a diagnosis and form a treatment plan. And over the years, researchers have built many clinical decision support systems, which have typically been purpose-built, with painstakingly written rules about symptoms, test thresholds, and medication interactions. As a…
