
biophysics

This article dives into a pretty wild leap in the study of three-dimensional (3D) chaotic microcavities. These are tiny structures […]

New models of the carotid artery can be personalized for different people, revealing subtle differences in stroke risk.
Conduct advanced spin-optical measurements on molecular spin qubits to develop novel quantum sensors for biosensing and nanoscale magnetic resonance. Focus on pulsed optically detected magnetic resonance at room temperature, working with chemically synthesised molecules. Operate within a multidisciplinary team using st...

Given the right conditions, certain types of cells are able to self-assemble into new lifeforms after the organism they were once part of has died.

Theoretical physicists are caricatured in the popular imagination as only involved in abstruse and difficult-to-imagine topics. But some of these theoretical physicists are involved in something closer…

Using lasers to trap and move particles changed the way we’re able to study microscopic life.

The Wistar Institute announces the appointment of Brian Fuglestad, Ph.D., as associate professor in the Center for Advanced Therapeutics (CAT). Fuglestad uses biophysical and biochemical approaches to study proteins at the molecular and atomic level.

The Wistar Institute announces the appointment of Brian Fuglestad, Ph.D., as associate professor in the Center for Advanced Therapeutics (CAT). Fuglestad uses biophysical and biochemical approaches to study proteins at the molecular and atomic level.

The Wistar Institute announces the appointment of Brian Fuglestad, Ph.D., as associate professor in the Center for Advanced Therapeutics (CAT). Fuglestad uses biophysical and biochemical approaches to study proteins at the molecular and atomic level.
Conventional image analysis loses vital structural information from orientation signatures within Fourier phase, easily disrupted by cellular rotation. Quantum Phase Bicoherence (QPBC) spectroscopy now overcomes this limitation, consistently resolving angular order and discriminating biological phenotypes across diverse imaging datasets. This new framework includes a built-in self-check via inher…

Being able to measure something plays a vital role in our ability to understand many phenomena. But measuring can often affect what we are trying to measure. This is particularly the case when measuring substances that are very small, soft or fragile. In a recent study published in PRX Life, a research team led by […]

Understanding the three-dimensional structure and mechanical response of biomolecules is key to uncovering their molecular mechanisms, particularly in contexts where force plays a regulatory role. Structural methods such as X-ray crystallography, Cryo-electron microscopy, and Nuclear Magnetic Resonance (NMR) spectroscopy provide high-resolution conformational data, while single-molecule force spe…
In El legado de Humberto Maturana y Francisco Varela: Desarrollos, desafíos y aplicaciones de la teoría autopoiética en el siglo XXI. Santiago de Chile: Ediciones Colegas. pp. 47-69. 2026This chapter examines whether teleological vocabulary can retain scientific legitimacy in biology without positing intentional purposes or sui generis properties. From a naturalistic standpoint, I defend a modest…
[Purpose] The qi-transformation (气化) theory in Chinese medicine describes the rhythmic adjustment of human physiological functions across seasons, but its driving source has long remained unidentified. Modern chronobiology has confirmed the molecular mechanism of the human biological clock but has not "why rhythms necessarily exist." Starting from the planetary dynamics framework established in t…
Nature Physics, Published online: 18 August 2026; doi:10.1038/s41567-026-03378-1 Creation and annihilation of topological defects are prevalent in active materials. It is now shown that in living systems with nematic order, polar propulsion breaks mirror symmetry during these processes.
Nature Communications, Published online: 17 August 2026; doi:10.1038/s41467-026-76703-0 Understanding molecular orientation is essential for unveiling biological structure and function. Here the authors develop a robust, high-fidelity framework (eGRL) for reconstructing complete 3D density and 3D orientation distributions of fluorescent molecules with polarized fluorescence microscopy.
Nonequilibrium Medicine; NEM; nonequilibrium thermodynamics; nonequilibrium biology; medical systems; energy flow; metabolic flux; dissipati Nonequilibrium Medicine; NEM; nonequilibrium thermodynamics; nonequilibrium biology; medical systems; energy flow

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