Hemadyne: accordion-inspired perfusion for microphysiological systems
Abhishek Jain
Nature Communications, Published online: 25 May 2026; doi:10.1038/s41467-026-73722-9 The physiological relevance and reproducibility of microphysiological systems is currently limited by perfusion systems. Here the authors engineer Hemadyne, an accordion music-inspired pump that mimics human blood flow, and apply it to study how aging-related flow waveforms impact vascular health.