Green tea–derived exosome-like nanoparticles attenuate oxidative stress–induced skin senescence via modulation of p38 MAPK signaling
Jae Youl Cho
IntroductionPlant-derived exosome-like nanoparticles (PDENs) have emerged as bioactive nanostructures capable of transferring molecular cargos across species; however, their mechanistic roles in mammalian stress-responsive signaling remain incompletely defined. In this study, we investigated the effects of green tea (Camellia sinensis (L.) Kuntze [Theaceae])–derived exosome-like nanoparticles (GtDENs) on oxidative stress–induced cellular dysfunction in human keratinocytes.MethodsTo do this, we e