Maturation-associated changes in Sertoli cells following in vitro culture of frozen-thawed prepubertal mouse testicular tissue
Ludovic Dumont
To preserve the fertility of prepubertal boys with cancer, testicular tissue can be cryopreserved in the hope of subsequently inducing their maturation after transplantation or in vitro culture for natural conception or medically assisted reproduction. Testicular tissue maturation procedures are currently at an experimental stage and mainly developed in animal models. Among these, in vitro sperm yield production in cultures of mouse prepubertal testicular explants is relatively low. Despite the