Galleria mellonella model recapitulates Staphylococcus aureus hemolysin toxicity and antibody-mediated mechanisms of protection
Emiliano Chiarot
The study of host-pathogen interactions in animal infection models has clarified mechanisms of bacterial pathogenicity and supported the development of preventive and therapeutic strategies. Although many virulence factors have been identified in vivo using mammals such as mice and rats, this work requires large numbers of animals. Over the past two decades, insect-based alternatives have gained popularity due to ethical and practical advantages. This study evaluated Galleria mellonella larvae a