Spiro-Azetidine Oxindoles as Long-Acting Injectables for Pre-Exposure Prophylaxis against Respiratory Syncytial Virus Infections J. Med. Chem. 2024, 67, 10986 Long-acting injectable (LAI) drugs, which you would expect to display efficacious plasma levels over a period of several months from 1-2 doses, have seen interest lately in numerous fields.[doi.org/10.1016/j.ebiom.2023.104764, doi.org/10.1038/s41578-021-00405-w, doi.org/10.1080/17425247.2022.2106213] This represents a significant divergence