Programmable artificial RNA condensates in mammalian cells

Elisa Franco
Nature Nanotechnology, Published online: 29 April 2026; doi:10.1038/s41565-026-02164-7 Modular RNA nanostar motifs spontaneously assemble into programmable synthetic condensates in the nucleus and cytoplasm, with RNA design controlling localization, sequence-specific target recruitment and orthogonal assembly.