Advances in plant polysaccharides in cancer therapy targeting ferroptosis
Li Huang
Cancer is a global health public issue with an increasing morbidity and mortality. Ferroptosis is a form of regulated cell death characterized by iron accumulation and lipid peroxidation, providing a novel and promising strategy for cancer treatment. Plant polysaccharides possess low toxicity, minimal side effects, and significant therapeutic potential, particularly in antioxidation, immune regulation, and cancer suppression. However, it is unknown that whether and how ferroptosis is involved in