IntroductionAlthough plantmicrobe systems have been studied for singlemetal contamination, little is known about their synergistic mechanisms under CdNi costress. Current studies often lack mechanistic explanations of microbial immobilization and plant physiological regulation, which this study aims to address.MethodsTo explore the remediation effect and intrinsic mechanism of the plant-microbe combined system on cadmium (Cd)-nickel (Ni) co-contaminated soil, Microbacterium algeriense (M. algeri