Toward high-stability quantitative carriers: development of superparamagnetic nanocarriers and a high-sensitivity mixing-frequency narrow-band magnetic particle imaging detection system

Shi Bai
IntroductionSuperparamagnetic iron oxide nanoparticles (SPIONs) have attracted extensive attention in recent years as visualizable and controllable organic nanocarriers. Magnetic particle imaging (MPI), as a quantitative imaging method, enables visual and quantitative characterization of carriers. The quantitative imaging capability of carriers is critically crucial for precise quantitative local drug concentrations. However, the alternating current susceptibility (ACS) of SPIONs is highly susce