Association between sevelamer use and outcomes in acute kidney injury with hyperphosphataemia: evidence from the MIMIC-IV
Changbo Liu
BackgroundHyperphosphataemia is consistently linked to adverse clinical outcomes in Acute Kidney Injury (AKI). Sevelamer, a non-calcium phosphate binder widely used in chronic kidney disease (CKD), has not been adequately evaluated for efficacy in AKI.MethodsWe performed a retrospective cohort analysis in the MIMIC- IV database. The association between sevelamer exposure and 28- day all-cause mortality was estimated using multivariable Cox models and propensity score matching (PSM).ResultsAfter