Oxidative stress response of Saccharomyces cerevisiae exposed to different molecular weight of polycyclic aromatic hydrocarbons
Panwad Sillapawattana
Polycyclic aromatic hydrocarbons (PAHs) are environmental contaminants that cause adverse health effects. This study investigated the toxic effect of different molecular weight PAHs on eukaryote model organism (Saccharomyces cerevisiae) exploiting oxidative stress biomarkers as endpoint indicators. Yeast cells were treated with environmentally relevant concentrations of phenanthrene (PHE), fluoranthene (FLA), and benzo[ghi]perylene (BghiP) for 24 h. Benzo[a]pyrene (BaP) was used as a positive co