Mitochondrial l -2-hydroxyglutarate is a physiological signalling metabolite
Navdeep S. Chandel
Nature, Published online: 20 May 2026; doi:10.1038/s41586-026-10564-x l-2-Hydroxyglutarate is identified as a legitimate physiological signalling metabolite, and control of its levels is essential for postnatal growth and survival and correct renal development and function.