physiology
The purpose of perspiration was a mystery in 1775, when English physician Charles Brian Blagden and a few inquisitive friends experimented on themselves by spending time in rooms heated to over 230° Fahrenheit.
Scientists have discovered that a key molecule released during exercise strengthens muscles, improves exercise performance and could be a therapeutic treatment for muscle damage caused by type 2 diabetes.
Just a few minutes of very hard exercise may trigger surprisingly large changes throughout the body. New research from Rockefeller University found that short bursts of all-out sprinting changed hundreds of substances circulating in the blood almost immediately. The response was much larger than researchers saw after far longer sessions of moderate exercise. Six 30-second […] The post Three Minut…
BackgroundChronic ankle instability (CAI) is a common sequela of lateral ankle sprain and is associated with recurrent injury, persistent functional limitations, sensorimotor deficits, and impaired postural control. However, how individuals with CAI adapt to graded and combined sensory feedback disruption remains unclear. This study aimed to determine whether individuals with CAI exhibit altered …
Scientific Reports, Published online: 10 August 2026; doi:10.1038/s41598-026-66004-3 Layer-specific stiffness dynamics in supraspinatus and trapezius muscles during a sustained isometric contraction
Platelet-rich plasma (PRP) exhibits substantial inter-individual variability, yet the physiological factors influencing its composition remain poorly defined. Most studies evaluate PRP as a homogeneous product, potentially masking associations between donor-related characteristics and platelet parameters. This study aimed to determine how key physiological factors influence whole blood (WB) and P…
IntroductionObjective assessment of hindlimb skeletal muscles in dogs remains challenging in small animal practice. This study aimed to use computed tomography (CT) to characterize hindlimb muscle distribution, identify optimal measurement levels, and evaluate the clinical applicability of a palpation-based hindlimb muscle condition score (hMCS) system.MethodsThis prospective observational study …
A newly published Finnish study demonstrates that, in addition to temperature, air humidity is a significant determinant of physiological strain during sauna bathing.
IntroductionRespiration is increasingly recognized as a key modulator of brain-body interactions, influencing both neural and autonomic dynamics. While prior work has demonstrated respiratory-driven entrainment, it remains unclear whether distinct phases of the breathing cycle give rise to different dynamical regimes of cortical activity.MethodsIn this study, we investigated respiratory-phase-dep…
A recent study reveals that spontaneous sighs do more than express boredom. They act as a physical reset button, restoring natural breathing rhythms and triggering a burst of physiological arousal during monotonous tasks.

The heart’s developed pressure (DP) in Langendorff heart experiments increases with preload via the Frank-Starling mechanism up to a critical transition point at which DP starts to decrease with preload. A similar behavior is found at the cellular level, where the tension developed by skinned cardiac fibers or myocytes in isometric tension test increases with sarcomere length up to a transition p…

Scientists drew blood from climbers near Everest’s summit and found oxygen levels that should have been lethal.
Astronauts shed roughly 1% of their bone mineral density per month in orbit — more than ten times the rate of severe osteoporosis on Earth. Here's what microgravity does to the skeleton, and why the bone doesn't fully grow back.

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