Poststroke anxiety and depression: epidemiology, mechanisms, and management strategies
Tairong Ai
Poststroke anxiety and depression (PSAD/PSAnx) are common and heterogeneous emotional disorders among stroke survivors, significantly impacting functional recovery, quality of life, and long term prognosis. Their pathogenesis is complex and multifactorial, involving neurobiological alterations, cognitive dysfunction, behavioral responses, and social environmental factors. Cognitive impairments, functional limitations, and insufficient social support can interact to amplify negative emotional res