The 35 Most Common Nitrogen-Containing Heterocycles in Drugs

A very high proportion of approved drugs contain nitrogen-containing heterocyclic structures. Taking the period from 2013 to 2023 (11 years) as an example, 82% of all approved drugs featured at least one nitrogen-containing heterocycle. This article presents the 35 most frequently occurring nitrogen-containing heterocyclic frameworks found among the 321 drugs approved during that time. - Pyridine is the most common nitrogen-containing heterocycle, ranking first overall. Fifty-four drugs include.