Subtyping a complex dementia
Liesbeth Aerts
Subtyping a complex dementia
A high-resolution view of frontotemporal dementia and TDP-43 accumulation
In nineteenth-century biology, few debates ran hotter than the one between “lumpers” and “splitters”. Lumpers preferred to group organisms into broad categories while splitters preferred to carve out ever more precise distinctions. As a consequence, botanists couldn't even agree on how many species the British flora contained. Joseph Dalton Hooker, one of the era's most prominent naturalists...