Self-limiting population suppression gene drive design in the West Nile vector mosquito, Culex quinquefasciatus
Feng Liu
Nature Communications, Published online: 26 May 2026; doi:10.1038/s41467-026-73641-9 Culex mosquitoes drive the spread of West Nile virus, yet controlling their populations remains challenging. Here, authors develop a self-limiting CRISPR-based genetic approach that converts female mosquitoes into sterile intersexes, enabling effective and confined population suppression.