Xyloglucan xylosyltransferase stem region mediates heterodimer formation

Olga A. Zabotina
Nature Communications, Published online: 16 May 2026; doi:10.1038/s41467-026-73329-0 The crystal structure of xyloglucan xylosyltransferases XXT2 and XXT5 reveals an obligate heterodimer, in which XXT2’s flexible stem binds the catalytic domain of XXT5. Heterodimer assembly is also mediated through stem-stem interactions in vivo.