FAU Review: Obesity and Alzheimer's Linked by Disease-Driving Metabolic Pathways
Florida Atlantic University
A review finds increasing evidence that obesity and Alzheimer's disease (AD) are biologically linked. The researchers highlight shared early metabolic disruptions involving mitochondrial dysfunction, chronic inflammation and abnormal signaling from fat tissue, which can affect brain health long before symptoms appear. The research also points to the gut-brain axis as a contributor to neurodegeneration. Together, the findings suggest AD risk may begin earlier than previously thought and support a