IntroductionAspirin-induced gastritis results from reduced prostaglandin synthesis and increased oxidative stress, compromising gastric mucosal integrity. While omeprazole effectively suppresses gastric acid secretion, it does not directly promote mucosal regeneration. Striatin, a bioactive fraction of Channa striata, has anti-inflammatory and regenerative properties and may enhance mucosal healing.PurposeThis study aimed to evaluate whether adjunctive striatin at escalating doses enhances the t