Hylocereus undatus flower inhibits lipopolysaccharide-induced acute lung injury in mice by regulating the gut-lung axis and inflammatory response

BackgroundHylocereus undatus flower (HUF), the dried flower of H. undatus (Haw.) Britton and Rose, was first recorded in the Lingnan Record of Medicinal Herbs and is now listed in the Dictionary of Traditional Chinese Medicines. As an established traditional remedy, HUF is primarily used to treat various pulmonary conditions, including pneumonia, asthma, and tuberculosis. Acute lung injury (ALI) represents a critical and common pathological manifestation underlying severe respiratory disorders.