Newly identified barrier cells seal off choroid plexus from CSF, rest of brain
Claudia López Lloreda
A previously unrecognized population of fibroblasts seals off the base of the choroid plexus—the network of blood vessels and cerebrospinal-fluid-producing epithelial cells that line the ventricles—from the cerebrospinal fluid (CSF) and the rest of the brain, a new study in mice shows.
The newly identified barrier provides an added layer of protection that is distinct from the well-known blood-brain barrier and the one that the epithelial cells form between the blood and the CSF.
The findings...