Uncovering risk factors in the exposome for early-onset colorectal cancer
Kimmie Ng
Nature Medicine, Published online: 30 April 2026; doi:10.1038/s41591-026-04369-8 The alarming rise in the incidence of colorectal cancer among younger individuals is probably due to environmental factors; epigenetic signatures of exposures may help uncover drivers of this trend, but questions remain.