A three-dimensional multi-modal foundation model for optical coherence tomography
Sheng Wang
Nature Biomedical Engineering, Published online: 24 April 2026; doi:10.1038/s41551-026-01662-2 The OCTCube models integrate optical coherence tomography and other imaging modalities to achieve state-of-the-art performance in predicting retinal diseases with strong generalizability across cohorts, devices and modalities.