Flow cytometry enables rapid evaluation of novel, new and niche antimicrobial agents
Aron Chakera
The global rise of multidrug-resistant bacteria necessitates the development of new antimicrobials and faster diagnostic tools. Conventional antimicrobial susceptibility testing is slow, relying on culture-based methods that delay effective treatment, often with fatal consequences in severe infections. In this study, we evaluate flow cytometry as a rapid, culture-minimal method to assess bacterial responses to six antimicrobials: ceftazidime-avibactam, meropenem-vaborbactam, cefiderocol, doxycyc