Effects of dexmedetomidine on perioperative neurocognitive disorders in elderly patients undergoing non-cardiac surgery: a scoping review
Yatao Liu
BackgroundPerioperative neurocognitive disorders (PNDs) are common and clinically significant complications in older surgical patients. Dexmedetomidine (DEX) has been investigated for neuroprotection; however, reported outcomes across PNDs subtypes remain inconsistent.MethodsFollowing PRISMA-ScR guidelines, we systematically searched PubMed, Embase, and Cochrane Library up to December 9, 2025. Eligible studies included patients aged ≥ 60 years undergoing non-cardiac surgery who received perioper