GalNAc-ASO: Targeted Liver Therapeutics
mybcs
Introduction to GalNAc-ASO Technology GalNAc (N-acetylgalactosamine)-conjugated antisense oligonucleotides (ASOs) utilize triantennary GalNAc ligands to bind the asialoglycoprotein receptor (ASGPR) on hepatocytes. This enables receptor-mediated endocytosis, delivering ASOs specifically to liver […]