Transcriptomic and experimental identification of immune- and telomere-related genes in pelvic organ prolapse
Chaoming Li
BackgroundPelvic organ prolapse (POP) is a prevalent disease among women, and immune cell and telomere have potential associations with the pathogenesis of POP. The identification and validation of immune cell-related genes (ICRGs) and telomere-related genes (TRGs) in POP are of great significance for elucidating its mechanisms, screening diagnostic key genes, and identifying therapeutic targets.MethodsIn this study, first, ICRGs were obtained based on immune infiltration and WGCNA; key genes re