The role of metabolic reprogramming in oocyte development: research progress and prospects

Jing Jin
IntroductionIn oocyte growth and development, metabolic reprogramming serves as a core process by which cells adjust their metabolic patterns—including glucose metabolism, lipid metabolism, and amino acid metabolism—to adapt to developmental cues, differentiation, and environmental stress. This reprogramming is essential for maintaining energy homeostasis and supporting biosynthesis. A synergistic and precisely regulated metabolic network provides the necessary energy, reducing equivalents, and