A porcine circovirus type 2d-based virus-like particle subunit vaccine effectively protects pigs against homologous challenge
Denian Miao
Porcine circovirus-associated disease (PCVAD), caused by pathogenic porcine circovirus type 2 (PCV2), remains one of the most economically devastating diseases in the global swine industry, and the continued emergence and predominance of the PCV2d genotype have raised concerns regarding the efficacy of currently available vaccine. In this study, a virus-like particle (VLP) subunit vaccine based on the PCV2d capsid protein was developed using a prokaryotic expression system, and its immunogenicit