Peripheral blood immune markers associated with negative symptoms in first episode psychosis: a systematic review
Fabiana Corsi-Zuelli
BackgroundNegative symptoms are a core feature of psychotic disorders, evident from the first episode of psychosis (FEP), and are strongly associated with poor functional outcomes. Increasing evidence suggests that immune dysregulation may contribute to negative symptom expression in FEP individuals; however, findings remain heterogeneous. This systematic review aimed to synthesise recent evidence on the association between peripheral blood immune markers and negative symptoms in FEP.MethodsA sy