psychosis

BackgroundSchizophrenia is a severe mental disorder associated with substantial disability. Although a growing body of evidence suggests that the duration of untreated psychosis (DUP) may influence prognosis, findings remains inconsistent.MethodsWe retrospectively analyzed 99 first-episode schizophrenia patients hospitalized at Shantou University Mental Health Center between 2015 and 2019. DUP wa…

BackgroundNegative symptoms are a core feature of psychotic disorders, evident from the first episode of psychosis (FEP), and are strongly associated with poor functional outcomes. Increasing evidence suggests that immune dysregulation may contribute to negative symptom expression in FEP individuals; however, findings remain heterogeneous. This systematic review aimed to synthesise recent evidenc…