Mycoplasma bovis infection alters small extracellular vesicle cargo derived from bovine endometrial epithelial cells cultured in static bioreactors
Mallory A. Ross
Mycoplasma bovis (M. bovis) is a pathogenic bacterium that causes significant production losses and welfare challenges in cattle. Eradication is challenging as M. bovis can infect host cells intracellularly, reducing detection from immunomodulatory cells. With an aim to improve diagnostics for post-eradication surveillance, small extracellular vesicles (sEVs) were used to identify novel biomarkers of M. bovis infection. Readily accessible in body fluids, these nanoparticles encapsulate protein c